Narrative

     Dr. Kukar’s lab studies the pathogenesis of neurodegenerative diseases to guide development of novel therapeutics and develop new strategies to treat neurodegenerative diseases. They focus on Frontotemporal dementia, Amyotrophic lateral sclerosis, and Alzheimer's disease. Dr. Kukar aims to understand the pathogenesis of these diseases by deciphering their molecular causes in order to identify new drug targets and ultimately therapeutic compounds. The lab uses a multidisciplinary approach ranging from cell culture, chemical biology, high-throughput screening, animal models, human Induced Pluripotent Stem Cells, clinical samples, to proteomics.